Postdoctoral Research Fellow in Computational Biology
Requirements
Candidates must have expertise in computational approaches for single-cell and single-nucleus RNA-seq data and an understanding of liver disease pathobiology. Strong communication skills and the ability to collaborate with wet lab scientists are required.
Job Description
Grade UE07: £41,064 - £48,822 per annum
School of Regeneration and Repair / Centre for Inflammation Research
Full-time: 35 hours per week
Fixed-term: 7 months
Together we can do great things. Be part of something bigger.
Join the University of Edinburgh and you’ll be making a difference to everything around you. Be part of something bigger – where you’ll do meaningful work, grow and progress, be rewarded and recognised, and benefit from our strong commitment to your wellbeing. There are so many reasons to join us.
The University of Edinburgh is a world-class organisation. We look for the best in the field across all disciplines and provide a working environment where academics can develop their careers and passion for their chosen subject area. We offer the full range of academic roles and have a genuine focus on our students’ performance and wellbeing.
The Opportunity:
We are looking for an enthusiastic and motivated postdoctoral research fellow in bioinformatics, to work on a project using cutting-edge single-cell and spatial transcriptomic approaches to understand the cellular and molecular mechanisms regulating liver fibrosis and to identify novel therapeutic targets for liver disease.
The successful candidate will work with Professor Prakash Ramachandran within the Centre for Inflammation Research at the University of Edinburgh. This 7-month post is funded by an MRC Senior Clinical Fellowship award to Professor Ramachandran. The post-holder will analyse single-cell and spatial transcriptomic data from human liver samples, to dissect cellular, molecular and spatial changes in the fibrotic liver. We anticipate that the combination of these approaches will identify novel approaches to selectively modulate pathogenic cell types as an antifibrotic therapy for patients with liver disease.
Your skills and attributes for success:
- Expertise in relevant computational approaches including analysis of single-cell and single-nucleus RNA-seq data
- An understanding of liver disease and/or fibrosis pathobiology
- An ability to work with wet lab scientists to design strategies to validate key findings from computational work
- Critical appraisal and analytical skills for interpreting qualitative and quantitative information
- Good verbal and written communication skills
- Self-motivation, initiative and ability to work both independently and as part of a team
This post is full-time (35 hours per week); however, we are open to considering flexible working patterns. We are also open to considering requests for hybrid working (on a non-contractual basis) that combines a mix of remote and regular on-campus working
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Please include the following documents in your application:
- CV
- Cover letter
People have always been at the heart of our work. As part of the University, you are a part of our community. We are looking for people with drive, determination, and a passion for what they do. We are a place where everyone is welcome and offer a range of policies and benefits designed to support you in building the right meaningful/personalised flexibility for you.
A career with us has a range of other benefits that can be tailored to your lifestyle:
- Variety every day
- Responsibility and autonomy within a supportive team
- Excellent benefits and support
- Contributing to the work and purpose of the University.
As a valued member of our team, you can expect:
A competitive salary.
An exciting, positive, creative, challenging and rewarding place to work.
To be part of a diverse and vibrant international community.
Comprehensive Staff Benefits, including generous annual leave entitlement, a defined benefits pension scheme, a wide range of staff discounts, family-friendly initiatives, and flexible work options. Check out the full list on our staff benefits page and use our reward calculator to discover the value of your pay and benefits.
Championing equality, diversity, and inclusion
The University of Edinburgh holds a Silver Athena SWAN award in recognition of our commitment to advance gender equality in higher education. We are members of the Race Equality Charter, and we are also Stonewall Scotland Diversity Champions, actively promoting LGBT equality.
Prior to any employment commencing with the University, you will be required to evidence your right to work in the UK. Further information is available on our right to work webpages.
Key dates to note
The closing date for applications is 3rd August 2026.
Unless stated otherwise, the closing time for applications is 11:59 pm (UK time). If you are applying from outside the UK, the closing time shown on our adverts will automatically adjust to your browser’s local time zone.
We anticipate that interviews will be held in late August 2026.
As a world-leading research-intensive University, we are here to address tomorrow’s greatest challenges. Between now and 2030 we will do that with a values-led approach to teaching, research and innovation, and through the strength of our relationships, both locally and globally.
The Centre for Inflammation Research (CIR) is a world-leading centre dedicated to understanding the mechanisms of inflammation and translating these insights into new therapies for inflammatory diseases. Part of The Institute for Regeneration and Repair (IRR), CIR brings together discovery science, clinical expertise, and cross-disciplinary innovation to improve human health across the lifespan.
Our mission is to transform the understanding and treatment of inflammation through cutting-edge research, inclusive collaboration, and impactful translation. By uniting discovery scientists, clinicians, chemists, engineers, and industry partners, we aim to develop innovative tools, therapies, and strategies that address pressing global health challenges.
Our research is structured across three interconnected themes - Infection and Immunity, Damage and Repair, and Experimental Medicine - providing a powerful framework for scientific collaboration and translational excellence.
Together, these themes investigate how inflammation starts, progresses, and resolves, and how it contributes to both health and disease. Through advanced experimental models, patient-focused research, and state-of-the-art technologies, we accelerate discovery and ensure our work leads to meaningful, real-world impact.
Centre for Inflammation Research website (https://inflammation-research.ed.ac.uk/) (opens in a new browser tab)
The Institute for Regeneration and Repair
The Institute for Regeneration and Repair (IRR) is cross-College with staff and students from the College of Medicine and Veterinary Medicine (CMVM) School of Regeneration and Repair (SRR) and the College of Science and Engineering (CSE), School of Biological Sciences and School of Chemistry. The School of Regeneration and Repair is one of six schools in CMVM.
At IRR our scientists and clinicians study tissue regeneration and repair to advance human health and reproductive outcomes. The Institute incorporates three leading research centres with a focus on regenerative medicine, inflammation and reproductive health. Our Director is Professor Stuart Forbes.
IRR has a 5-year income of over £200M and is a collaborative hub for commercial, clinical and academic endeavour. Based at Edinburgh BioQuarter we bring together world leading research expertise to drive understanding and deliver clinical and translational outcomes.
IRR has a work environment built on trust and encourages the very best talent from all backgrounds and at all levels to join us. A diverse team strengthens our ability to innovate and support cutting-edge world leading research. Supporting and empowering our team at all levels is central to our approach.
Our team is ambitious, acts with integrity and demonstrates commitment to progress and impact. We aim to achieve excellence in all that we do, always being principled, considerate and respectful.
Institute for Regeneration and Repair website (https://regeneration-repair.ed.ac.uk/ ) (opens in a new browser tab)
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